Sculptra is made of Poly(L-lactide) (PLLA), a biocompatible, biodegradable material. PLLA mimics human collagen. It is regenerative in that it also stimulates your body to create its own new collagen. As we age, we lose 10% of our collagen production with each decade. That means that at 40 years old, you have a 40% decrease in collagen production as compared to when you were born. At 50 years old, you’ll lose 50%, and so on. Sculptra is the only FDA-approved filler that produces results that last over 2 years; the longevity of results is in large part due to regenerative effects.