Think of prolotherapy as the opposite of a cortisone shot. With a cortisone injection you have immediate pain relief, your immune response is completely stunted, your joint degenerates at a faster pace, and your pain comes back with a vengeance a month or 2 later.

With prolotherapy, you will experience some soreness in the first few days as the body begins to regenerate. Pain relief begins in about one week and the maximum treatment effect results in several weeks as the body regenerates new cells and your joint regains stability and strength.